Publications

Here is a list of selected publications from the Molecular Psychiatry Lab at the University of Fribourg, arranged by year.

2026

Hinney, B., Jost, S., Toto, S., Seifert, J., Erfurth, A., Greil, W., Horvath, A., Grohmann, R. and Hasler, G. (2026.) Cross-national differences in methylphenidate utilization in primarily adult psychiatric inpatients. The World Journal of Biological Psychiatry, pp.1-12.

2025

Diehl, V. J., Calder, A. E., & Hasler, G. (2025). The helioscope effect: A new framework for evaluating trauma-related memory processing in psychedelic experiences. Journal of Psychopharmacology, 02698811251397306.

Buchmann, A., Hase, A., Ritter, C. J., Müller, S. T., Haynes, M., Huber, S., … & Hasler, G. (2025). A Data-Driven Decomposition of Anxiety. Psychopathology.

Calder, A.E., Diehl, V.J., Hasler, G. (2025). Traumatic Psychedelic Experiences. In: Current Topics in Behavioral Neurosciences. Springer, Berlin, Heidelberg. https://doi.org/10.1007/7854_2025_579

Yousefi, P., Lietz, M. P., O’Higgins, F. J., Rippe, R. C. A., Hasler, G., van Elk, M., & Enriquez-Geppert, S. (2025). Acute effects of psilocybin on attention and executive functioning in healthy volunteers: a systematic review and multilevel meta-analysis. Psychopharmacology, 1-26.

Calder, A. E., Qualls, C., Hasler, G., Elmiger, D., & Strassman, R. (2025). The Hallucinogen Rating Scale: Updated factor structure in a large, multi-study sample. Biological Psychiatry Global Open Science, 100436.

2024

Calder, A. E., Hase, A., & Hasler, G. (2024). Effects of psychoplastogens on blood levels of brain-derived neurotrophic factor (BDNF) in humans: a systematic review and meta-analysis. Molecular Psychiatry, 1-14.

Calder AE, Rausch B, Liechti ME, Holze F, Hasler G. Naturalistic psychedelic therapy: The role of relaxation and subjective drug effects in antidepressant response. Journal of Psychopharmacology. 2024;0(0).

Calder, A., & Hasler, G. (2024). Validation of the Swiss Psychedelic Side Effects Inventory: Standardizing reporting of adverse effects in studies of psychedelics and MDMA. Journal of Affective Disorders, 365, 258-264.

Kupferberg, A., & Hasler, G. From Antidepressants and Psychotherapy to Oxytocin, Vagus Nerve Stimulation, Ketamine and Psychedelics: How Established and Novel Treatments Can Improve Social Functioning in Major Depression. Frontiers in Psychiatry, 15, 1372650.

Hasler G, Inta D; Emerging Perspectives on Neuroprotection. Psychother Psychosom 11 October 2024; 93 (5): 285–291.

Rouaud, A., Calder, A. E., & Hasler, G. (2024). Microdosing psychedelics and the risk of cardiac fibrosis and valvulopathy: Comparison to known cardiotoxins. Journal of Psychopharmacology, 02698811231225609.

2023

Hasler, G., Majerus, S., & Vollenweider, S. (2023). Mystik im Labor. Die experimentelle Psychedelika-Forschung fordert das Verständnis von Mystik heraus. Jahrbuch für Biblische Theologie Volume, 38, 1.

Tuura, R., Buchmann, A., Ritter, C., Hase, A., Haynes, M., Noeske, R., & Hasler, G. (2023). Prefrontal Glutathione Levels in Major Depressive Disorder Are Linked to a Lack of Positive Affect. Brain Sciences, 13(10), 1475. https://doi.org/10.3390/brainsci13101475

Suker, S., Mihov, Y., Wolf, A., Mueller, S. V., & Hasler, G. (2023). Behavioral response to catecholamine depletion in individuals with schizophrenia and healthy volunteers. Schizophrenia Bulletin Open. https://doi.org/10.1093/schizbullopen/sgad023

Kupferberg, A., & Hasler, G. (2023). The social cost of depression: Investigating the impact of impaired social emotion regulation, social cognition, and interpersonal behavior on social functioning. Journal of Affective Disorders Reports, 14, 100631. https://doi.org/10.1016/j.jadr.2023.100631

Calder, A., Mock, S., Friedli, N., Pasi, P. R., & Hasler, G. (2023). Psychedelics in the treatment of eating disorders: Rationale and potential mechanisms. European Neuropsychopharmacology, 75, 1–14. https://doi.org/10.1016/j.euroneuro.2023.05.008

Calder, A., & Hasler, G. (2023). Extrapharmacological safety topics in Psychedelic-Assisted Psychotherapy. JAMA Psychiatry, 80(8), 761. https://doi.org/10.1001/jamapsychiatry.2023.1031

Ponomarenko P, Seragnoli F, Calder A, Oehen P, Hasler G. Can psychedelics enhance group psychotherapy? A discussion on the therapeutic factors. Journal of Psychopharmacology. 2023;37(7):660-678. doi:10.1177/02698811231155117

Hase, A., Haynes, M., & Hasler, G. (2023). Using simple economic games to assess social orienting and prosocial behavior in adolescents with autism spectrum disorder. Autism Research, 16(6), 1199–1209. https://doi.org/10.1002/aur.2931

2022

Solmi, M., Thompson, T., Estradé, A., Agorastos, A., Radúa, J., Cortese, S., Dragioti, E., Leisch, F., Vancampfort, D., Thygesen, L. C., Aschauer, H., Schloegelhofer, M., Aschauer, E., Schneeberger, A. R., Huber, C. G., Hasler, G., Conus, P., Cuénod, K. Q. D., Von Känel, R., . . . Correll, C. U. (2023). Validation of the Collaborative Outcomes study on Health and Functioning during Infection Times (COH-FIT) questionnaire for adults. Journal of Affective Disorders, 326, 249–261. https://doi.org/10.1016/j.jad.2022.12.022

Guglielmo, R., De Filippis, R., Ouanes, S., & Hasler, G. (2022). Editorial: The glutamate hypothesis of mood disorders: Neuroplasticity processes, clinical features, treatment perspectives. Frontiers in Psychiatry, 13. https://doi.org/10.3389/fpsyt.2022.1054887

Ritter, C., Buchmann, A., Müller, S., Volleberg, M., Haynes, M., Ghisleni, C., Noeske, R., Tuura, R., & Hasler, G. (2022). Evaluation of prefrontal Γ-Aminobutyric acid and glutamate levels in individuals with major depressive disorder using proton magnetic resonance spectroscopy. JAMA Psychiatry, 79(12), 1209. https://doi.org/10.1001/jamapsychiatry.2022.3384

Guglielmo, R., & Hasler, G. (2022). The neuroprotective and neuroplastic potential of glutamatergic therapeutic drugs in bipolar disorder. Neuroscience & Biobehavioral Reviews, 142, 104906. https://doi.org/10.1016/j.neubiorev.2022.104906

Calder, A., & Hasler, G. (2022). Towards an understanding of psychedelic-induced neuroplasticity. Neuropsychopharmacology, 48(1), 104–112. https://doi.org/10.1038/s41386-022-01389-z

Miskowiak, K. W., Yalın, N., Seeberg, I., Burdick, K. E., Balanzá‐Martínez, V., Del Mar Bonnín, C., Bowie, C. R., Carvalho, A. F., Dols, A., Douglas, K., Gallagher, P., Hasler, G., Kessing, L. V., Lafer, B., Lewandowski, K. E., López‐Jaramillo, C., Martı́nez-Arán, A., McIntyre, R. S., Porter, R., . . . Stokes, P. (2022). Can magnetic resonance imaging enhance the assessment of potential new treatments for cognitive impairment in mood disorders? A systematic review and position paper by the International Society for Bipolar Disorders Targeting Cognition Task Force. Bipolar Disorders, 24(6), 615–636. https://doi.org/10.1111/bdi.13247

Hasler, G. (2022). Toward the “helioscope” hypothesis of psychedelic therapy. European Neuropsychopharmacology, 57, 118–119. https://doi.org/10.1016/j.euroneuro.2022.02.006

Hasler, G., Hopwood, C. J., Jacob, G., Brändle, L. S., & Schulte-Vels, T. (2014). Patient-reported outcomes in borderline personality disorder. Dialogues in Clinical Neuroscience, 16(2), 255–266. https://doi.org/10.31887/dcns.2014.16.2/ghasler

Hase, A., Erdmann, M., Limbach, V., & Hasler, G. (2022). Analysis of recreational psychedelic substance use experiences classified by substance. Psychopharmacology, 239(2), 643–659. https://doi.org/10.1007/s00213-022-06062-3

Buchmann, A., Ritter, C., Müller, S., Haynes, M., Ghisleni, C., O’Gorman, R. L., & Hasler, G. (2022). Associations between heart rate variability, peripheral inflammatory markers and major depressive disorder. Journal of Affective Disorders, 304, 93–101. https://doi.org/10.1016/j.jad.2022.02.017

2021

Ritter, C., Buchmann, A., Müller, S., Hersberger, M., Haynes, M., Ghisleni, C., Tuura, R., & Hasler, G. (2021). Cerebral perfusion in depression: Relationship to sex, dehydroepiandrosterone sulfate and depression severity. NeuroImage: Clinical, 32, 102840. https://doi.org/10.1016/j.nicl.2021.102840

Guglielmo, R., Miskowiak, K., & Hasler, G. (2021). Evaluating endophenotypes for bipolar disorder. International Journal of Bipolar Disorders, 9(1). https://doi.org/10.1186/s40345-021-00220-w

Stocker, K., Hasler, G., & Hartmann, M. (2021). Letter to the editor: Are ketamine-induced subjective bodily experiences associated with antidepressant effects? A sensation of floating and a sensation of lightness are not the same – A comment on Acevedo-Diaz et al. Journal of Psychiatric Research, 137, 454–455. https://doi.org/10.1016/j.jpsychires.2021.03.017

Martin‐Soelch, C., Guillod, M., Gaillard, C., Recabarren, R. E., Federspiel, A., Mueller‐Pfeiffer, C., Homan, P., Hasler, G., Schoebi, D., Horsch, A., & Gomez, P. (2021). Increased Reward-Related activation in the ventral striatum during stress exposure associated with positive affect in the daily life of young adults with a family history of depression. preliminary findings. Frontiers in Psychiatry, 11. https://doi.org/10.3389/fpsyt.2020.563475

Research Gate Profiles

Prof. Dr. Gregor Hasler

Dr. Adrian Hase

Abigail Calder